Intraoperative Needle-Based Refractive Index Measurement of ex vivo Human Breast Tissue

Adam M. Zysk, Daniel L. Marks, Freddy T. Nguyen, Jan G. Kotynek, Frank J. Bellafiore, Patricia A. Johnson, Kendrith M. Rowland, Stephen A. Boppart. Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, OSA Technical Digest 2007-09-16

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Refractive index measurements offer high contrast between normal fatty tissue and diagnostically significant structures. We have developed a needle-based device capable of measuring internal tissue properties. We present preliminary clinical data from human specimens.
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