2025 MIT Health Science Forum: Treatment Effectiveness, New Biology Using AI – Enabled Nanosensor Technology (MIT Industrial Liaison Program – Startup Exchange)

Determining Treatment Effectiveness, Discovering New Biology Using AI – Enabled Nanosensor Technology
Freddy Nguyen
CEO & Co-Founder, Nine Diagnostics
See more of the 2025 MIT Health Science Forum here: https://ilp.mit.edu/Health25
Nine Diagnostics Joins American Cancer Society’s BrightEdge Entrepreneurs Program

Nine Diagnostics, a leader in AI-enabled nanosensor technology, has been selected to participate in the American Cancer Society’s BrightEdge Entrepreneurs Program, a highly selective initiative designed to accelerate the most promising oncology-focused startups. This selection marks another significant milestone for Nine Diagnostics as it continues to drive innovation in cancer treatment selection, dosing, optimization, and monitoring.
Nine Diagnostics Selected for Merck Digital Sciences Studio Cohort 3

Arnold and Mabel Beckman Foundation – March 30, 2017
2017 Beckman Postdoctoral Fellow
Massachusetts Institute of Technology
Research: Development of nanosensors for in-vivo monitoring of cancer therapeutics
Freddy Nguyen, MD/PhD and Nine Diagnostics Win Novo Nordisk Golden Ticket at Pitch Event

Arnold and Mabel Beckman Foundation – March 30, 2017
2017 Beckman Postdoctoral Fellow
Massachusetts Institute of Technology
Research: Development of nanosensors for in-vivo monitoring of cancer therapeutics
Nine Diagnostics Wins Novo Nordisk Golden Ticket for LabCentral Residency

Arnold and Mabel Beckman Foundation – March 30, 2017
2017 Beckman Postdoctoral Fellow
Massachusetts Institute of Technology
Research: Development of nanosensors for in-vivo monitoring of cancer therapeutics
Fluorescence-based detection of protein aggregation and fiber optic-based benchtop instrument
MIT Healthcare Innovation

Healthcare innovation ecosystem at MIT and the Greater Boston Area
Nine Diagnostics

Determining treatment effectiveness, discovering new biology using AI enabled nanosensor technology.
A faster path to the most effective treatment with better outcomes. We develop holistic profiles based on a patient’s personal health data, demographics, social determinants of health, and other relevant factors pertinent to the ultimate outcomes.
Multidimensional datasets are acquired from fluorescent emissions using an array of nanoscale sensing elements that detect health abnormalities and signals of treatment effectiveness in small patient samples.
Role: Chief Executive Officer, Co-Founder
Prevented Health

Delivering immersive digital care journeys for addiction prevention for people being treated for ADHD, anxiety, or pain. We help improve mental health, track wellbeing, and connect with care teams and peers starting with our AI-driven Prescription Companion to reduce the risk of addictive medicines.
Role: Chief Operating Officer, Co-Founder
Nature Digital Medicine: Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer

The majority of biomedical research is funded by public, governmental, and philanthropic grants. These initiatives often shape the avenues and scope of research across disease areas. However, the prioritization of disease-specific funding is not always reflective of the health and social burden of each disease. We identify a prioritization disparity between lung and breast cancers, whereby lung cancer contributes to a substantially higher socioeconomic cost on society yet receives significantly less funding than breast cancer. Using search engine results and natural language processing (NLP) of Twitter tweets, we show that this disparity correlates with enhanced public awareness and positive sentiment for breast cancer. Interestingly, disease-specific venture activity does not correlate with funding or public opinion. We use outcomes from recent early-stage innovation events focused on lung cancer to highlight the complementary mechanism by which bottom-up “grass-roots” initiatives can identify and tackle under-prioritized conditions.
MIT Hacking Medicine

The mission of MIT Hacking Medicine is to infect, energize, and empower a diverse, global community in healthcare entrepreneurship and innovation to scale medicine to attack and solve healthcare problems.
Role: Co-Director (2018-2020), Research Group Lead (2018-Present)
Project Prana Foundation

Project Prana Foundation was born with the mission to innovate with a holistic approach that was cost-effective and patient-centered.
The iSAVE (Individualized System for Augmenting Ventilator Efficacy) represented more than a collaborative effort to solve the immeidate challenge at hand. This innovation represents a deeper motivation to address inequities and inadequacies in healthcare.
Role: Advisor
