Freddy T. Nguyen, MD, PhD

Research Fellow @ Massachusetts Institute of Technology, Transfusion Medicine Fellow @ Dartmouth-Hitchcock Medical Center

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy
Oliver Jonas, Jeon Woong Kang, Surya P. Singh, Alex Lammers, Freddy T. Nguyen, Ramachandra R. Dasari, Peter T. C. So, Robert Langer, Michael J. Cima. Analyst 2018-10-08

Full Text
We describe a label-free approach based on Raman spectroscopy, to study drug-induced apoptosis in vivo. Spectral-shifts at wavenumbers associated with DNA, proteins, lipids, and collagen have been identified on breast and melanoma tumor tissues. These findings may enable a new analytical method for rapid readout of drug-therapy with miniaturized probes.
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Physician-scientist with extensive experience developing and translating nanotechnologies and biomedical optical technologies from the bench to clinic in areas of genetics, oncology, and cardiovascular diseases. Extensive leadership experience in community building in healthcare innovation, research, medical, and physician-scientist communities.

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MIT Hacking Medicine – Publications

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Email: freddytn@mit.edu

Arnold O. Beckman Postdoctoral Fellow
Institute for Medical Engineering and Science

Research Fellow, MIT Office of Innovation
Former Co-Director, MIT Hacking Medicine
Regional Director – Europe, MIT Hacking Medicine
Co-Director, MIT COVID-19 Challenge
Co-Director, MIT Hacking Racism Challenge

Massachusetts Institute of Technology
77 Massachusetts Avenue
Cambridge, MA 02139

Email: Freddy.T.Nguyen@hitchcock.org

Transfusion Medicine Fellow
Department of Pathology and Laboratory Medicine

Geisel School of Medicine
Dartmouth Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756