Freddy T. Nguyen, MD, PhD

Transfusion Medicine Fellow @ Dartmouth-Hitchcock Medical Center

Research Fellow @ Massachusetts Institute of Technology

Physician-scientist with extensive experience developing and translating nanotechnologies and biomedical optical technologies from the bench to clinic in areas of genetics, oncology, and cardiovascular diseases. Extensive leadership experience in community building in healthcare innovation, research, medical, and physician-scientist communities.

Needle-based refractive index measurement using low-coherence interferometry

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Adam M. Zysk, Steven G. Adie, Julian J. Armstrong, Matthew S. Leigh, Alexandre Paduch, David D. Sampson, Freddy T. Nguyen, Stephen A. Boppart. Optics Letters 2007-02-15
We present a novel needle-based device for the measurement of refractive index and scattering using low-coherence interferometry. Coupled to the sample arm of an optical coherence tomography system, the device detects the scattering response of, and optical path length through, a sample residing in a fixed-width channel. We report use of the device to make near-infrared measurements of tissues and materials with known optical properties. The device could be used to exploit the refractive index variations of tissue for medical and biological diagnostics accessible by needle insertion.
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